Thursday, October 29, 2009

Mutants: On Genetic Variety and the Human Body

Over the summer, I was staying with some friends at their flat in London -- a lovely couple I have known for years. He also works on medieval monsters, and has just finished his Ph.D. working on the subject. His bookshelf was therefore of great interest to me. They had to go to work the morning I left, so I was to let myself out. I did so, "borrowing" their copy of Armand Marie Leroi's Mutants: On Genetic Variety and the Human Body (as well as their Oystercard for the London tube... Both will be returned, I swear...).

And I am so glad I did! First off, the Oystercard saved me several pounds on the ride to Heathrow. More importantly, though, the book is fascinating! It moves back and forth between the history of medicine -- how various genetic issues were viewed in the past -- and contemporary genetic science. Some of the denizens of the text are familiar to folks (like me) interested in these matters, Pygmies and "thyroid giants," for example. But many were completely new and some quite shocking. Fibrodysplasia ossificans progressiva, for example, causes bone to grow in response to injuries, rather than muscle and skin, so that the body slowly is overtaken by a second, ossified skeleton.

The volume is well-illustrated, and written in a very accessible manner. Even this humble art historian was able to follow most of the scientific explanations. Really, I learned a great deal about human genetics and physiology from the book.

Leroi is rarely sensationalistic, and generally quite sympathetic to the issues he covers, rightly attempting, when possible, to see these genetic "abnormalities" not as diseases (What, exactly, is "diseased" with being a certain height? Having an uncommon shape? Being between the two poles of gender?) but as part of the great, sweeping variety that composes the human species throughout the globe. This one is highly recommended, though do be forewarned: Some of the content is rather haunting, and will stay with you for days.

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